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BIO811S - BIOINFORMATICS - 2ND OPP- JULY 2023 |
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nAmlBIA unlVERSITY
OF SCIEn CE Ano TECHn OLOGY
FACULTY OF HEALTH, NATURAL RESOURCES AND APPLIED SCIENCES
SCHOOL OF NATURAL AND APPLIED SCIENCES
DEPARTMENT OF BIOLOGY, CHEMISTRY AND PHYSICS
QUALIFICATION : BACHELOR OF SCIENCE {HONOURS)
QUALIFICATION CODE: 08BOSC
LEVEL: 8
COURSE CODE: BIO8115
COURSE NAME: BIOINFORMATICS
SESSION: JULY 2023
DURATION: 3 HOURS
PAPER: THEORY
MARKS: 120
SECOND OPPORTUNITY/SUPPLEMENTARY EXAMINATION QUESTION PAPER
EXAMINER{S) Prof Percy Chimwamurombe
MODERATOR: Dr Jean-Damascene Uzabakiriho
INSTRUCTIONS
1. Answer ALL the questions.
2. Write clearly and neatly.
3. Number the answers clearly.
PERMISSIBLE MATERIALS
Non-programmable Calculators
ATTACHMENTS
None
THIS QUESTION PAPER CONSISTS OF 2 PAGES (Including this front page)
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SECTIONA:
[60 MARKS]
1. Using examples, write short notes on the following term used in
Bioinformatics:
a. BLAT
b. BLOB
c. Phylogenetic tree
d. Gene ontology
e. Bankit
f. FASTA.
(5 marks)
(5 marks)
(5 marks)
(5 marks)
(5 marks)
(5 marks)
2. Give a practical use of genomic circuits in single genes.
3. Use the example of a human disease complex to describe
the concept of integrating single gene circuits.
(10 marks)
(10 marks)
4. Describe any complex gene circuits, which you have studied.
(10 marks)
Section B: Essays
[60 MARKS]
1. Describe the lactose operon and how it can be used to explain
a single gene circuit.
(30 marks)
2. Write a detailed essay on BLAST.
(30 marks)
2