© In human hosts, the parasites form tissue
A cysts, most commonly in the skeletal muscle,
myocardium, brain, and eyes; diagnosis is typically
achieved by serology, although tissue cysts can be
observed in stained biopsy specimens
A infective stage
A = Diagnostic stage
© Blood transfusion or organ
A transplantation from infected host
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© Transpiacental
transmission
Avneay eeeen’ @® Diagnosis of congenitat
gondit DNA in amniotic fluid
(oma
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meat from
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that
tissue
» cysts
© Oocysts differentiate into tachyzoites, then
localize in neural and muscle tissue and
differentiate into tissue cyst bradyzoites
=
— Tissue yt
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intermediate —
Aw ingest soil,
water, or plants
contaminated
with oocysts
O Cats ingest intermediate
hosts that harbor tissue
dee tect cysts; they can also be
ingesting sporulated
ootysts
@ Humans ingest food or water
A contaminated with cat feces or are
exposed to contaminated environmental
samples (e.g., fecal-contaminated soil,
litter box of infected cat)
Fecal oocysts
@
@ Unsporulated oocysts
are shed in cat feces
Livestock and wild game ingest
sporulated oocysts in the environment
Figure 1. The Life Cycle of Toxoplasma species.
6.3.1 Describe how man is infected by this parasite.
(4)
6.3.2 Discuss the infective stage of this parasite to man.
(7)
6.3.3 In the human host, the Parasite forms tissue cysts, most commonly in which
organs?
(3)
6.3.4 Describe how this parasite can be diagnosed.
6.3.5 Describe how this parasitic infection can be prevented.
(2)
END OF EXAMINATION
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