BPP521S - BASIC PATHOPHYSIOLOGY - 2ND OPP - JAN 2023


BPP521S - BASIC PATHOPHYSIOLOGY - 2ND OPP - JAN 2023



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r
"
nAmlBIA unlVERSITY
OF SCIEnCE
TECHnDLOGY
FACULTYOF HEALTH,APPLIEDSCIENCESAND NATURALRESOURCES
DEPARTMENTOF HEALTHSCIENCES
QUALIFICATION : BACHELOROF SCIENCEIN HEALTHINFORMATION SYSTEMMANAGEMENT
QUALIFICATIONCODE: 07BHIS
COURSENAME: BASIC
PATHOPHYSIOLOGY
SESSION:JANUARY 2023
LEVEL: 5
COURSECODE: BPP521S
PAPER:THEORY
DURATION: 3 HOURS
MARKS: 100
EXAMINER:
SECONDOPPORTUNITYEXAMINATION QUESTIONPAPER
Dr Roswitha Mahalie
MODERATOR: Dr Elizabeth Van Der Coif
INSTRUCTIONS
1. Answer ALL the questions.
2. Write clearly and neatly.
3. Number the answers clearly.
4. Write all answers in the answer booklet provided.
PERMISSIBLEMATERIALS
1. SCIENTIFICCALCULATOR.
THIS QUESTION PAPERCONSISTSOF 5 PAGES(Including this front page)

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QUESTION 1
SECTIONA
[10 MARKS]
Evaluate the statements in each numbered section and select the most appropriate answer or
phrase from the given possibilities. Each question carries 1- mark.
1.1 The death unwanted cells resulting from activation of intracellular signalling cascades is
referred to as:
A. Anaplasia
B. Apoptosis
C. Chloasma
D. Melasma
1.2 An overall weight loss and generalized weakness in the body is also referred to as?
A. Hypolipidemia
B. Cachexia
C. Intracellular accumulation
D. adipose tissue disorder
1.3 Which of the following
A. Haematoma
B. Petechiae
C. Ecchioses
D. Purpura
is not part of the aetiology of haemorrhage?
1.4 A replacement of a mature cell type by a different mature cell type, is called:
A. Dysplasia
B. Hyperplasia
C. Hypertrophy
D. Metaplasia
1.5 An active process resulting from arteriolar dilation and increased blood flow to an organ is
called:
A. Viremia
B. Osmosis
C. Hyperemia
D. Haemostasis
1.6 Study of all factors that cause a disease, is called:
A. Clinical Manifestation
B. Pathology
C. Aetiology
D. Prognosis
1.7 A mild degree of unconsciousness from which the patient can be awakened with words
or shaking is called:
A. Stupor
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B. Drowsiness
C. Syncope
D. Gait disorders
1.8 The adult person has approximately_
A. 3000
B. 206
C. 300
D. 250
bones of various shapes and sizes:
1.9 The presence of many microorganisms
A. Subclinical Infection
B. Nosocomial infections
C. In-hospital infections
D. Clinical Infection
in health facilities
is referred to as:
1.10 Examples of genetic de-arrangement
A. Down Syndrome (trisomy 21)
B. Haemophilia
C. Paget Disease
D. Sickle cell Anaemia
includes the following
except:
QUESTION 2
[10 MARKS]
Fill the missing words in the statements below. Each answer earns one (1) mark.
2.1
2.2
2.3
2.4
2.5
2.6
2.7
2.8
2.9
2.10
______
is an infection affecting the renal tubules, pelvis, and calices.
______
is a condition caused by abnormal accumulation of cerebrospinal fluid
(CSF)in the cerebral ventricular system.
______
is when the roof of the mouth develops in two separate halves (before
birth)
______
disorders are found in children, especially when there is an interference
with the deposition of bone in the growth plates.
______
is defined as bleeding from the nose usually due to rupture of small
blood vessels in the anterior part of the nasal septum
______
is farsightedness that develops if the eyeball and the image is focussed
behind the retina.
______
are painless, cystic masses containing sperm.
_____
happens when supporting pelvic structures relaxes and the cervix sags
downward into the vagina.
______
refers to a loss of lung volume caused by inadequate expansion of air
spaces.
______
is an infection of the larynx with accompanying hoarseness, leading to
the inability to talk in an audible voice.
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[.
QUESTION 3
(30 MARKS)
3.1 Disease develops when cell structure and function change. Describe the types of cellular
adaptation
(14)
3.2 Figure 1 below illustrates one of the different vascular disorders. Respond to the
following questions.
3.2.1 Identify and define the vascular disorder depicted below.
(4)
Fig 1: Example of a vascular disorder
3.2.2 Type the identified vascular disorder.
(6)
3.2.3 Six (6) clinical manifestations of disorder.
(6)
SECTION B
QUESTION 4
(30 MARKS]
4.1 Briefly define the following concepts:
(8)
4.1.1 Blood-brain-barrier
(2)
4.1.2 Active immunity
(2)
4.1.3 Inflammation
(2)
4.1.4 Glaucoma
(2)
4.2 Briefly describe the stages of the General Adaptation Syndrome (GAS) which is caused by a
general stress response.
(6)
4.3 Pain is experienced when specific nerve endings are stimulated.
4.3.1 Discuss the 3-step process of pain in the human body.
(6)
4.3.3 Classification of pain.
(10)
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QUESTION 5
SECTION C
(20 MARKS]
5.1 Indicate whether the following statements are True or False. Each answer earns one (1)
mark.
(5)
5.1.1
5.1.2
5.1.3
5.1.4
5.1.5
The brachia! artery in the arm is used to measure blood pressure.
Nephroptosis occurs when the kidney becomes detached from its position and
moves freely beneath the diaphragm.
Astigmatism develops from an irregular curvature in the cornea or lens
Osteoporosis is referred to as the degenerative or 'wear-and-tear'
non-inflammatory joint disease
Hyperaldosteronism (Conn syndrome) is defined as an excessive excretion
of aldosterone by the pituitary gland.
5.2 Ms. Pearl, a 44-year-old mother of 5 children, was caught in a fire in her corrugated
house whilst they were all asleep. The whole family was rescued from the house, but
she had mixed burns on her arms, chest and back except her hands and face. It was
determined by the paramedics that she had full-thickness burns.
5.2.1 Using the rules-of-nines, calculate the approximate area of full-thickness burns
on her right arm, chest and back.
(5)
5.2.2 Differentiate between deep partial-thickness and full thickness burns.
(10)
All the best!!!!
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