EPD711S - EPIDEMIOLOGY 3 - 1ST OPP - JUNE 2022


EPD711S - EPIDEMIOLOGY 3 - 1ST OPP - JUNE 2022



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nAm I BIA u n IVE RS ITV
OF SCIEnCE Ano TECHnOLOGY
FACULTYOF HEALTH,APPLIEDSCIENCESAND NATURAL RESOURCES
DEPARTMENT OF HEALTHSCIENCES
QUALIFICATIONS:BACHELOROF ENVIRONMENTALHEALTHSCIENCESB, ACHELOROF SCIENCEIN
HEALTHINFORMATIONSYSTEMSMANAGEMENT, BACHELOROF HUMAN NUTRITION
QUALIFICATION CODE: 08BOHS, 07BHIS,
08BOHN
LEVEL: 7
COURSECODE: EPD711S
COURSENAME: EPIDEMIOLOGY3
SESSION:
JUNE 2022
PAPER:
THEORY
DURATION: 3 HOURS
MARKS:
100
FIRSTOPPORTUNITY EXAMINATION QUESTION PAPER
EXAMINER(S) DR LARAIAKU-AKAI
MODERATOR: DR ROSWITHAMAHALIE
INSTRUCTIONS
1. Answer ALL the questions.
2. Write clearly and neatly in the spaces provided.
PERMISSIBLEMATERIALS
1. Scientific calculator
2. Statistical tables (attached)
THIS QUESTION PAPERCONSISTSOF 9 PAGES(including this front page)

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Question 1
Select the most appropriate answer from the options provided.
1.1 Which of the following can be obtained from retrospective studies:
a) Attributable risk
b) Prevalence rate
c)
Relative risk
d) Odd's ratio
(20 marks)
(1)
1.2 These are all discrete variables except:
a) Cars in the garage
b) Boys in the classroom
c) Height in metres
d) Computer hardware delivered
(1)
1.3 The total number of cases of a disease at a given point in time in a given population is:
a) Incidence
b) Prevalence
c)
Epidemiology
d) Attack rate
(1)
1.4. Seasonal variation of a disease can be assessed by:
a) Comparing incidence of disease
b) Comparing prevalence of disease
c)
Using mortality rates
d)
Using survival rates
(1)
1.5. All are disadvantages of case-control studies except:
a)
Incidence rate cannot be ascertained
b) Bias can be introduced in selection of controls
c)
It is unsuitable for studying rare diseases
d)
It is reliant on respondents' memory or reliable record keeping
(1)
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1.6. Which of the following statements is not true about cross-sectional studies?
a) Based on a single examination at one point in time
b) More useful for chronic diseases
c)
Provides very little information about the natural history of disease
d) Can help in identifying risk factors for disease
(1)
1.7. All are advantages of cohort studies except:
a) Several outcomes related to exposure can be studied simultaneously
b) Bias is minimized
c)
It is suitable for studying rare diseases
d)
Dose response to exposure can be studied
(1)
1.8. Which of the following statements is true about ecological studies?
a) The study units are the individuals within the population
b) More useful for chronic diseases
c)
It makes comparison between large populations
d)
It demonstrates trends over time
(1)
1.9 Learners' annual academic performance were compiled and ranked, as "first",
"second", "third", "fourth", and so on. This belongs to what scale of measurement?
a) nominal
b) ordinal
c) interval
d) ratio
(1)
1.10 The normal distribution curve is dependent on:
a) Mean and sample
b) Mean and median
c) Median and standard deviation
d) Mean and standard deviation
(1)
Indicate which of the following is true orfalse:
1.11 The difference between the proportion of cases interviewed and the proportion of
controls interviewed could cause selection bias.
(1)
3

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1.12
1.13
1.14
1.15
1.16.
1.17
1.18
1.19
1.20
Descriptive studies could be used to generate hypothesis.
(1)
Ecological studies are used to monitor trends of events over a long period of time
in the same population.
(1)
By matching the controls to the cases on age, it is ensured that age will not be a
confounder.
(1)
Restricting the study to non-smokers introduces smoking as a confounder in the
study.
(1)
A pie chart is useful in presenting qualitative data.
(1)
An advantage of the cohort design compared to a case-control study design is
that in a cohort study one can address multiple outcomes.
(1)
Participant observation can be used to collect quantitative data.
(1)
Cross-sectional studies are limited by their lack of generalisability, but are
powerful in that they directly measure risk.
(1)
Cross-sectional studies cannot directly assesscausal inference because they
measure disease and exposure in a person at the same point in time.
(1)
Question 2
Explain the following terms used in health research:
(Each correct answer earns 2 marks)
2.1 Bias
2.2 Variable
2.3 Hypothesis
2.4 Confounding
2.5 Autonomy
2.6 Volunteer effect
2.7 Type 2 error
2.8 Confidence interval
2.9 Probability sampling
2.10 Critical region
(20 marks)
Question 3
(20 marks)
3.1 Identify each of the following as either qualitative (specify nominal or ordinal) or
quantitative (specify discrete or continuous).
3.1.1. Coliform count in water sample
(2)
3.1.2. Level of satisfaction with health services
(2)
3.1.3. Weight in kg
(2)
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3.1.4. Numbers of days admitted in hospital
(2)
3.1.5. Gender
(2)
3.2 Select the most suitable sampling method for the following situations (One method for
each situation):
3.2.1 Selection of cases of individuals with sexually transmitted infections
(2)
3.2.2 Selection of participants for a survey on obesity among NUSTstudents (2)
3.2.3 Selection of health officials for interview on evaluation of community
health interventions in Windhoek.
(2)
3.3 Select the most suitable study design for the following situations:
3.3.1 A municipality wants to determine the acceptability of a do-it-yourself
water purification method among residents in an informal settlement.
They also need to determine the sources of water and occurrence of
water borne diseases among the residents.
(2)
3.3.2 The municipality wants to determine if the do-it-yourself water
purification method improved the quality of drinking water among
residents in an informal settlement. After providing the water
purification method to a random sample of residents of the area,
they collect water samples from both those who utilised the water
purification method and a random sample of those who did not utilise
the method and compare the quality of the water.
(2)
Question 4
(20 marks)
4.1 Outline the characteristics of the X2-distribution.
(4)
4.2 Highlight four (4) potential sources of error in studies and how to overcome each
error mentioned.
(8)
4.3 Discussfocus group discussions.
(8)
Question 5
(20 marks)
5.1 The weight of children under 5 years of age is distributed closely normally, with a mean
of 17 kg and standard deviation of 6 kg. A Nutritionist is trying out a certain diet for its
impact on nutritional status among children under-5. A random sample of 42 children
placed on the diet were weighed after 2 months, and an average weight of 21 kg was
obtained. Does the diet make a difference in the average weight of the under-S's?
(8)
5

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5.2 A group of occupational hygienists follow a g·roup of workers in a noisy factory who
consistently make use of PPEto protect their ears from noise for 18 years compared to
another group of workers who do not use of PPEto protect their ears from noise. The
occupational hygienists want to determine if there is a difference in the incidence of
hearing loss between the two groups over the 18 year period. Of 110 workers who
consistently make use of PPE,10 develop hearing loss and of 60 workers who do not use
PPEconsistently, 15 develop hearing loss.
5.2.1 State the study design used.
(1)
5.2.2 Design a table and insert the information above.
(4)
5.2.3 Analyse the results of the study and conclude on the findings.
(7)
Good luck!!!
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Z table
z
.00
.01
.02
.03
.04
.OS
.06
.07
.08
.09
.0
.5000
.5040
.5080
.5120
.5160
.5199
.5239
.5279
.5319
.5359
.I
.5398
.5438
.5478
.5517
.5557
.5596
.5636
.5675
.5714
.5753
.2
.5793
.5832
.5871
.5910
.5948
.5987
.6026
.6064
.6103
.6141
.3
.6179
.6217
.6255
.6293
.6331
.6368
.6406
.6443
.6480
.6517
.4
.6554
.6591
.6628
.6664
.6700
.6736
.6772
.6808
.6844
.6879
!
I
J
.5
.6915
.6950
.6985
.7019
.7054
.7088
.7123
.7157
.7190
.7224
I
I
.6
.7257
.7291
.7324
.7357
.7389
.7422
.7454
.7486
.7517
.7549
.7
.7580
.761 I
.7642
.7673
.7704
.7734
.7764
.7794
.7823
.7852
.8
.7881
.7910
.7939
.7967
.7995
.8023
.8051
.8078
.8106
.8133
.9
.8159
.8186
.821~
.8238
.8264
.8289
.8315
.8340
.8365
.8389 I
l
I
1.0
.8413
.8438
.8461
.8485
.8508
.8531
.8554
.8577
.8599
.8621 I
1.1
.8643
.8665
.8686
.8708
.8729
.8749
.8770
.8790
.8810
' .8830 I
I
1.2
.8849
.8869
.8888
.8907
.8925
.8944
.8962
.8980
.8997
.9015
1.3
.9032
.9049
.9066
.9082
.9099
.9115
.9131
.9147
.9162
.9177
1.4
.9192
.9207
.9222
.9236
.9251
.9265
.9279
.9292
.9306
.9319
1.5
.9332
.9345
.9357
.9370
.9382
.9394
.9406
.9418
.9429
I .9441 I
1.6
.9452
.9463
.9474
.9484
.9495
.9505
.9515
.9525
.9535
i .9545
1.7
.9554
.9564
.9573
.9582
.9591
.9599
.9608
.9616
.9625
.9633
i
!
I
1.8
.9641
.9649
.9656
.9664
.9671
.9678
.9686
.9693
.9699
.9706 i
;
1.9
.9713
.9719
.9726
.9732
.9738
.9744
.9750
.9756
.9761
I .9767
I
I
2.0
.9772
.9778
.9783
.9788
.9793
.9798
.9803
.9808
.9812
.9817 I
I
2.1
.9821
.9826
.9830
.9834
.9838
.9842
.9846
.9850
.9854
I .9857
2.2
.9861
.9864
.9868
.9871
.9875
.9878
.9881
.9884
.9887
.9890
!
!
2.3
.9893
.9896
.9898
.9901
.9904
.9906
.9909
.9911
.9913
.9916 I
2.4
.9918
.9920
.9922
.9925
.9927
.9929
.9931
.9932
.9934
.9936
l
i
2.5
.9938
.9940
.9941
.9943
.9945
.9946
.9948
.9949
.9951
.9952 I
2.6
.9953
.9955
.9956
.9957
.9959
.9960
.9961
.9962
.9963
.9964
'I
!
2.7
.9965
.9966
.9967
.9968
.9969
.9970
.9971
.9972
.9973
I .9974
2.8
.9974
.9975
.9976
.9977
.9977
.9978
.9979
.9979
.9980
.9981
l
I
2.9
.9981
.9982
.9982
.9983
.9984
.9984
.9985
.9985
.9986
.9986
i'
;
3.0
.9987
.9987
.9987
.9988
.9988
.9989
.9989
.9989
.9990
I .9990
I
I
3.1
.9990
.9991
.9991
.9991
.9992
.9992
.9992
.9992
.9993
I .9993
3.2
.9993
.9993
.9994
.9994
.9994
.9994
.9994
.9995
.9995
.9995
I
I
3.3
.9995
.9995
.9995
.9996
.9996
.9996
.9996
.9996
.9996
i .9997 !
3.4
.9997
.9997
.9997
.9997
.9997
.9997
.9997
.9997
.9997
! .9998
I
7

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t Table
cum. prob
one--tail
t ..511
0.50
t.TS
0.25
t.311
t .ll!
0.20 0.15
t.Jltt
t_g5
t.111s
t
t.JiOs t1m t.-~
0.10 0.05 0.025 0.01 0.005 0.001 0.00051
two-tails 1.00 0.50 0.40 0.30 0.20 0.10 0.05 0.02 0.01 0.002 0.001
df
0.00.() \\.000
t.376
1.963 3.078 6.314
12.71 3 .82 63.66 318.31 636.62
2 0.000 0.816
1.00t
1.388 1.8813 2.920 4.31l3 l>.885 Q.li25 22..327 31.599
3 0.000 0.765 0.978 1.250
.638 2.353 3.182 4.541 5.841 0.2 5 2.924
4 0.000 0.74
0.941 1.190
.533 2. 32 2.776 3.747 4.&4
7.173 8.6 0
5
6
o:na 0.000 0.727
o:000
0.Q20 1. 15<:l t.470 2.015
Q:.906- (134, t'.+10 1.~3
2.::,71
2447
3.3-65 4.032
'3r.143 :no1
5.sn
5~
8.800
5.851}"
1
8
9
ro
11
tl®O
_o~-
0.000·
0.000
0:000
.. ,.too o0.:7r1o1e~
Q~
0,..889
,UHl
t:tos
t41_5
l.387
0:700
0.700
0.697
0.$3:
0.87Q
. 0.876
;;._003l..338732
l.088 L363
1.m f.995
.,.&.60
i;:2!..~3M.
2.900
2.896
'2,2tfa 2.821
1._8'11'
"2.784•-
1.7tl6 2.20i
2.718
3.4~
f.a.5.5
3..250
'3-.:16~
3:1oe·
U8!> 5.408
4.501: ' '·,\\!J.1.)4l,
-4..2Q7 4.7811
4.14;1 4.Ji87·
4.025 4.437
12 0.000 0.695 0.873 1.083 1.356 1.782 2.179 2.881 3.055 3.B30 4.3 8
13 0..000 0.694 0.870 t.079
.350
14 0.000 0.692 0.888 1.076 1.345
p:.ooo 15 0.000 0.69
0.8136 1.074
.341
ffl
0;600 0.1385 1.07t 1.~37
17 ·0.000,: 0.600 -0.863
ta 0.000 o:68.6 0.862
19 0.000 0:.688 o..~
2'() 01>00·
0.860
21 0.000 0.686 o.ssg
1:t)&f .3'33
1.0~7 1.330
.0136' 1.328
1.0M'
1~063
t.325 ..
.323
22 0.000
23 0.000
0.686
0.68~
0.858
0.858
1.06
.32
.oeo 1.3 HI
24 0.000 0.685 0.857 1.059
.318
25 0.000 0.884 0.856
.058 1.316
26
Z1
-0.000
0.000
0:.-684
0~84
Q.~
e.aM
·t.058 .315
1.-314
28 OA,00 o.683 0.855 .056
.;113
2Q OJlOO o.~ 0.854 j.056
-~1"1
30 . ,0.000· 0.683 0.~54 t.055 1:310·
40 0.000 0.68
0.851 1.050 1.3<03
00 0.000 0.679 0.848 1.045 1.2Q6
80 0.000 0.678 0.846 1.043 1.2Q2
1.771
1.781
t.753
1.746
1.740
t.rn
i.m
1.~5
1.721
1.717
1.714
1.711
1.708
1.700
1.7W
1.701
1.009
1.697
1.684
t.671
l.i:364
2.160 2..850 3.0'2.
2. 45 2.624 2.977
2. 31 2.602 2.947
2.11.0 ··2.583'2.821
- 10: 2.56-7 2,1198
,lL1C.1 2.562 2.578
200$ 2...539 .2..1361
,2.osa i~8
.284&
2.080 2.518 2.831
2.074 2.508 2.8 9
2.059 2.500 2.807
2.084 2:.492 2.7g7
- 2.050
:2,~·
2.485 2787
,2;_47g_ WJJ
2.052 .2.~73 i77'1
2.048 2.AW 2.763
2..045 2Ad2 2.756
2.q,t~ 2.457 2.750:
2.021 2.423 2.704
2.000 2.300 2.6130
1.990 2.374 2.639
3.852 4.221
3.787 4.140
3.733 4.073
3-.686 4.015
3..646 3..005
3$10 3.922
a.~m:1 3.~
3.552
3.527
3.850
3.8Q
:t505 3.7~2
3.485 3.768
3.467 3.745
3.450
3..~
3.42l
3.725
':j,_7{Jf
~.e.oo;
3..408 3.674
a.3s;fo 3.659",
a.ass 3.~
3.307 3.551
3.232 3.4e,O
3.195 3A 6
100
1000
z,
0.000
0.00.Q
·0;000
0%
0.677
0.675
0.674
50%
0.845
0.842
0.842.
60%
1.042
.037
t.038
70%
l.2QO 1.660 1.984
.282 1.648 1.002
uaz· l.64!l 1-;000
80% 90% 95%
Confidence Level
2.364
2.330
'2.326
98%
2.626
2.581
3.174
3.0'JS
3.300
3.300
2'.;576 3.000 -3-~1
ggo,{, .99.8% 99.9%
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