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CEB601S - CELL BIOLOGY - 2ND OPP - JULY 2023 |
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nAmlBIA unlVERSITY
OF SCIEnCE Ano TECHnOLOGY
FACULTYOF HEALTH,APPLIEDSCIENCESAND NATURALRESOURCES
SCHOOLOF NATURALAND APPLIEDSCIENCES
DEPARTMENTOF BIOLOGY,CHEMISTRYAND PHYSICS
QUALIFICATION: BACHELOR OF SCIENCE(MAJOR AND MINOR)
QUALIFICATION CODE: 07BOSC
LEVEL:6
COURSECODE: CEB601S
COURSENAME: CELLBIOLOGY
SESSION:JULY 2023
PAPER:THEORY
DURATION: 3 HOURS
MARKS: 100
SUPPLEMENTARY/SECONDOPPORTUNITYQUESTION PAPER
EXAMINER
DR LAMECH MWAPAGHA
MODERATOR DR JEYA KENNEDY
INSTRUCTIONS
1. Answer ALL the questions.
2. Write clearly and neatly.
3. Number the answers clearly.
4. All written work MUST be done in BLUEor BLACKink.
PERMISSIBLEMATERIAL
Scientific Calculator
THIS QUESTION PAPERCONSISTSOF EIGHT (8) PAGES
(Including this front page)
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SECTIONA: MULTIPLECHOICEQUESTIONS
[20]
• There are 20 multiple choice questions in this section. Each question carries 1 mark.
• Answer ALLquestions by selecting the LETTERwith the correct answer.
1. What is the minimum distance for the eye to focus any object?
A. 11 cm
B. 25 cm
C. 32 cm
D. 42 cm
2. The movement of water molecules from an area of high concentration to an area of low
concentration through a semipermeable membrane is known as;
A. Active Transport
B. Diffusion
C. Phagocytosis
D. Osmosis
3. Which of the following statements about the TCA cycle is correct?
A. Oxygen is used to oxidise the acetyl group carbons of acetyl-CoA in the TCA cycle
B. Oxygen is not used in the TCA cycle, so the cycle can occur in anaerobic conditions
C. The TCA cycle produces the water that is formed during the complete oxidation of glucose
D. Three molecules of NADH and one molecule of FADH2 are produced in one turn of the TCA
cycle
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4. Which statement correctly outlines some of the main events in photosynthesis?
A. A SC carbohydrate accepts carbon dioxide and is then reduced by NADPH derived
from photophosphorylation.
B. A 3C carbohydrate is regenerated and reduced by hydrogen molecules derived from
photophosphorylation.
C. Photolysis uses light to produce reduced NADP and oxygen which are used to reduce
a 3C carbohydrate.
D. Photolysis produces NADPH and ATP which are used to reduce a SCcarbohydrate.
5. In which phase of the cell cycle is DNA replicated?
A. Gl phase
B. S phase
C. G2 phase
D. M phase
6. All of the following are part of a prokaryotic cell except;
A. DNA
B. A cell wall
C. Ribosomes
D. An endoplasmic reticulum
7. In a plant cell, DNA may be found;
A. Only in the nucleus and mitochondria
B. Only in the nucleus and chloroplasts
C. In the nucleus, mitochondria, and chloroplasts
D. In the nucleus, mitochondria, chloroplasts, and peroxisomes
8. Which of the following comes under the category of cell surface receptor?
A. Enzyme linked receptors
B. Ion-channel linked receptors
C. G protein linked receptors
D. All of these
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9. Primer used for the process of polymerase chain reaction are ______
_
A. Single stranded DNA oligonucleotide
8. Double stranded DNA oligonucleotide
C. Single stranded RNA oligonucleotide
D. Double stranded RNA oligonucleotide
10. At what temperature do annealing of DNA and primer takes place?
A. 42°
8. 54°
C. 74°
D. 96°
11. Which of the following statements about the generation of ATP in the electron transport chain is
correct?
A. The generation of ATP from ADP coupled to electron transfer occurs by substrate level
phosphorylation as in glycolysis
8. Electron transport generates a proton gradient across the outer mitochondrial membrane
C. ATP synthase generation of ATP involves a rotating structure outside the inner mitochondrial
membrane
D. ATP synthase generation of ATP involves a rotating structure inside the inner mitochondrial
membrane
12. Which of the following microscopy techniques, relies on the specimen interfering with
the wavelength of light to produce a high contrast image, without the need for dyes or
any damage to the sample?
A. Conventional bright field light microscopy
8. Phase contrast microscopy
C. Electron microscopy
D. Fluorescence microscopy
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13. Which structure is the site of the synthesis of proteins that may be exported from the
cell?
A. Rough ER
8. Lysosomes
C. Plasmodesmata
D. Free cytoplasmic ribosomes
14. What are scaffolding proteins?
A. Microtubular protein arrays that allow lipid-soluble hormones to get from the cell
membrane to the nuclear pores
8. Large molecules to which several relay proteins attach to facilitate cascade effects
C. Relay proteins that orient receptors and their ligands in appropriate directions to
facilitate their complexing
D. Proteins that can reach into the nucleus of a cell to affect transcription
15. A gas is most soluble in a liquid at
A. Low temperature and low pressure.
8. High temperature and high pressure.
C. High temperature and low pressure.
D. Low temperature and high pressure.
16. Synaptic signaling between adjacent neurons is like hormone signaling in which of the
following ways?
A. It sends its signal molecules through the blood.
8. It requires calcium ions.
C. It requires binding of a signaling molecule to a receptor.
D. It persists over a long period.
17. Which of the following is NOT a fat-soluble vitamin?
A. Vitamins A
8. Vitamins 8
C. Vitamins D
D. Vitamins K
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18. The ribonucleotide polymer (S')GTGATCAAGC(3')could only form a double-stranded structure
with;
A. (S')CACTAGTTCG(3')
B. (S')CACUAGUUCG(3')
C. (S')CACUTTCGCCC(3')
D. (S')GCTTGATCAC(3')
19. Which of the following glycosidic linkage found in maltose?
A. Glucose (a-1- 2B) Fructose
B. Glucose (al- 4) Glucose
C. Galactose (Bl - 4) Glucose
D. Glucose (Bl -4) Glucose
20. Potassium cyanide interferes with the formation of ATP. The use of potassium cyanide
reduces the rate at which molecules of a certain chemical enter the cell. Select the
process by which the molecules would normally enter the cell.
A. Simple diffusion
B. Active transport
C. Facilitated diffusion
D. Osmosis
END OF SECTIONA
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SECTION B
• There are FIVE (5) questions in this section. Answer all Questions.
Question 1
a) State SIX (6) important enzymes responsible for Krebs cycle reactions.
b) Briefly describe FOUR (4-)demerits of the confocal microscope.
c) State FIVE (5) functions of the Nervous tissue.
Question 2
a) Explain the role of each of the following enzymes involved in DNA replication
I. DNA Polymerase:
II. Primase:
Ill. Helicase:
IV. Topoisomerase:
b) What is the fate of absorbed glucose by tissues in Eukaryotes?
c) State FIVE (5) applications of Polymerase Chain Reaction.
Question 3
a) State the FOUR (4) major Eukaryotic tissues types.
b) Briefly describe EIGHT (8) functions of epithelial cells.
[80]
[19]
(6)
(8)
(5)
(15]
(4)
(6)
(5)
(20]
(4)
(16)
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Question 4
[14]
a) Using the line structure below draw both the a- form and P-form cyclic structures.
(8)
CH20H
=O
HO
H
H
OH
H
,:)H
CH2C•H
b) Briefly delineate the main types of muscle tissue
(6)
Question 5
[12]
a) Describe the TWO (2) types of Heterochromatin
(4)
b) Briefly discuss the aerobic cellular respiration as a metabolic pathway that breaks down glucose
and produces ATP
(8)
END OF SECTION B
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PERIODICTABLEOF THE ELEMENTS
18
l
2
H
1.00794
2
13
14
15
He
16
17 4.00260
3
4
56
7
8 9 10
Li Be
B C N 0 F Ne
6.941 9.01218
10.81 12.011 14.0067 15.9994 18.9984 20.179
11 12
13 14 15 16 17 18
Na Mg
Al Si p s Cl Ar
22.9898 24.305 3
4
5
6
7
8
9
10
11
12 26.9815 28.0855 30.9738 32.06 35.453 39.948
19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
K Ca Sc Ti V Cr Mn Fe Co. Ni Cu Zn Ga Ge As Se Br Kr
39.0983 40.08 44.9559 47.88 50.9415 51.996 54.9380 55.847 58.9332 58.69 63.546 65.38 69.72 72.59 74.9216 78.96 79.904 83.8
i
37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54
Rb Sr y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe
\\Q
0....,
85.4678 87.62 88.9059 91.22 92.9064 95.94 (98) 101.07 102.906 106.42 107.868 112.41 114.82 118.69 121.75 127.6 126.9 131.29
'°
55 56 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86
Cs Ba Lu Hf Ta w Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn
132.905 137.33 174.967 178.49 180.948 183.85 186.207 190.2 192.22 195.08 196.967 200.59 204.383 207.2 208.908 (209) (210) (222)
87 88 103 104 105 106 107 108 109 110 111 112
114
11(;
118
Fr Ra Lr Rf Db Sg Bh Hs Mt Uun Uuu Uub
Uuq
(223) 226.025 (260) (261) (262) (263) (264) (265) '268) (269) (272) (269)
Uuh
Uuo
Lantbanides: 57 58 59 60 61 62 63 64 65 66 67 68 69 70
La Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb
138.906 140.12 140.908 144.24 (145) 150.36 151.96 157.25 158.925 162.50 161.930 167.26 166.934 173.04
Actinides:
89 90 91 92 93 94 95 - 96 97 - 98 99 100 101 102
Ac Th Pa u Np Pu Am Cm Bk Cf Es Fm Md No
227.028 232.038 231.036 238.029 237.048 (244) (243) (247) (247) (251) (252) (257) (258) (259)