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ANP621S - ANATOMICAL PATHOLOGY 2B - 1ST OPP - NOV 2022 |
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nAmlBIA unlVERSITY
OF SCIEn CE Ano TECHn OLOGY
Faculty of Health, Applied Sciences and Natural Resources
Department of Health Sciences
QUALIFICATION: BACHELOROF MEDICAL LABORATORYSCIENCES
QUALIFICATION CODE: 08BMLS
LEVEL: 6
COURSE: ANATOMICAL PATHOLOGY2B
COURSE CODE: ANP621S
DATE: NOVEMBER 2022
SESSION: THEORY
DURATION: 3 HOURS
MARKS: 100
EXAMINER(S)
MODERATOR:
FIRST OPPORTUNITY EXAMINATION QUESTION PAPER
Ms Roselin Tsauses
Ms Ndeshipewa Hamatui - Valombola
INSTRUCTIONS
1. Answer all questions.
2. Please write neatly and legibly.
3. Do not use the left side margin of the exam paper. This must be allowed for the
examiner.
4. No books, notes and other additional aids are allowed.
5. Mark all answers clearly with their respective question numbers.
Permissable material
Non programmable calculator is allowed.
THIS EXAMINATION PAPER CONSISTS OF 6 PAGES (Excluding this front page)
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Section A (10 marks)
Question 1
[10]
1.
Evaluate the statements in each numbered section and select the most
appropriate answer. Write "true" or "false" next to the corresponding
number.
1.1 Schwann and Schleiden published their cell theory in 1838.
a) True
b)
False
1.2 Cytology (also known as cytopathology) involves examining cells from
bodily tissues or fluids to determine a diagnosis.
a)
True
b)
False
1.3 The internal genitalia consists of the vagina, cervix, uterus, fallopian
tubes, ovaries and the clitoris.
a) True
b)
False
1.4 The cervix is the neck of the uterus, the lower, narrow portion where it
joins with the upper part of the vagina.
a) True
b)
False
1.5 Cytolysis only occurs in cells which have cell walls.
a)
True
b)
False
1.6 Identification of abnormal epithelial cells is the first step in learning
how to screen cervical samples.
a)
True
b)
False
1.7 Benign tumors do not necessarily turn into malignant tumors.
a) True
b)
False
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1.8 Adults are more likely than children to develop blastomas.
a) True
b)
False
1.9 Cell growth and cell division should always occur together.
a) True
b)
False
1.10 A common finding in cervicovaginal smears is reparative change as
a result of a variety of processes that may involve the glandular,
metaplastic, and squamous epithelium.
a) True
b)
False
Section B (37 marks)
Question 2
(15]
2.1 Study the diagram of the female reproductive system below and answer
the questions. Write the correct answer next to the corresponding number
and letter.
·2.1.1 Recognize the parts labelled A- E.
{5)
2.1.2 Relate the parts labelled A- Eto its respective epithelial lining.
(10)
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Question 3
[22]
3.1 Correlations between cytology and histology have identified certain
features as most useful for distinguishing normal and neoplastic cells.
Demonstrate your understanding of the above statement by explaining
what this entails.
(10)
3.2 Using your answers obtained in question 3.1 as a guide, tabulate
prominent characteristic cytological features of the following
epithelial cells:
3.2.1 Superficial squamous cell
(3)
3.2.2 Intermediate squamous cell
(3)
3.2.3 Parabasal cells
(3)
3.2.4 Basal cells
(3)
Section C (29 marks)
Question 4
4.1 Discuss the distinct anatomical regions of the cervix and its cytological
significance in detail.
4.2 /\\pp!y your knowledge to justify the presence of lactobacilli in the
vaginal canal from a cytological point of view.
[14]
{10)
(4)
Question 5
5.1 Study the following slides showing agents of infection seen in
cervical samples. Identify the agents and substantiate your answer
from a cytological perspective. Write your answer next to the
corresponding number.
[15]
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5.1.1
5.1.2
5.1.3
(3)
(3)
(3)
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5.1.4
5.1.5
(3)
(3)
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Section D (24 marks)
Question 6
[8]
6.1 Describe the cause of the following artefacts and contaminants:
6.1.1 Fixation artefacts
(1)
6.1.2 Corn-flake artefacts
(1)
6.2 Report the cytological pattern seen in women experiencing the following
stages of menopause:
6.2.1 Early menopause
(2)
6.2.2 Post-menopause
(2)
6.2.3 Late post-menopause
(2)
Question 7
7.1 Summarize the pathogenesis of cervical cancer.
7.2 Sketch a scenario explaining how ovarian cancer metastasizes using
appropriate terminology and how doctors can tell that it is cancer that
has metastasized.
[16]
(10)
(6)
Good luck!
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