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ANP621S-ANATOMICAL PATHOLOGY 2B-JAN 2020 |
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NAMIBIA UNIVERSITY
OF SCIENCE AND TECHNOLOGY
Faculty of Health and Applied Sciences
Department of Health Sciences
QUALIFICATION: BACHELOR OF MEDICAL LABORATORY SCIENCES
QUALIFICATION CODE: O8BMLS
LEVEL: 6
COURSE: ANATOMICAL PATHOLOGY 2B
COURSE CODE: ANP621S
DATE: JANUARY 2020
SESSION:
DURATION: 3 HOURS
MARKS: 100
SUPPLEMENTARY/SECOND OPPORTUNITY EXAMINATION QUESTION PAPER
EXAMINER(S) | Mr Simon Israel
MODERATOR: | Dr Munyaradzi Mukesi
INSTRUCTIONS
1. Answer all questions.
2. Please write neatly and legibly.
3. Donotuse the left side margin of the exam paper. This must be allowed for the
examiner.
4. No books, notes and other additional aids are allowed.
5. Mark all answers clearly with their respective question numbers.
Permissable material
Non programmable calculator is allowed.
THIS QUESTION PAPER CONSISTS OF 5 PAGES (Including this front page)
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SECTION A (30 MARKS)
QUESTION 1
[15]
Evaluate the statements in each numbered section and select the most appropriate
answer or phrase from the given possibilities. Write the appropriate letter next to the
number of the statement/phrase.
1.1 What is the meaning of the word Cytology?
(1)
a. Research of different cells.
b. Aspecific stain used for staining of tissue cells.
c. The medical and scientific study of cells.
1.2 Palisaded strips are associated Pseudo-stratified columnar cells.
(1)
a. True
b. False
1.3 Each cell is a complex system consisting of many different building blocks
enclosed in membrane bags.
(1)
a. True
b. False
1.4 The cell sizes may vary depending on:
(1)
a. The cell type and circumstances.
b. The host.
c. Volume of plasma in the body.
1.5. Procaryotes are:
(1)
a. Multicellular.
b. Multicellular with nucleus present.
c. Unicellular with nucleus absent.
1.6
Eukaryotic cells have a nucleus containing:
(1)
a. Eosinophilic matter.
b. All the cell's DNA.
c. All the minerals needed to form a cell.
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1.7. + The definition for Meiosis is:
(1)
a. Type of cell division that results in two daughter cells each having the
same number and kind of chromosomes as the parent nucleus, typical
of ordinary tissue growth.
b. The process of reproduction of gametes or sex cells containing one half
of the chromosomes from each respective parent
c. The division of a cell into four daughter cells with different genetic
material.
1.8 The following are parts of the female internal organs:
(1)
a. Femur, cervix, uterus
b. Fallopian tubes, gall bladder
c. Uterus, vagina, cervix, ovaries
1.9 — Stratified squamous mucosa is found in:
(1)
a. Fallopian tubes, vagina
b. Vagina, cervix
c. Ovaries, fallopian tubes
1.10 The nuclear stain haematoxylin stains the nuclei red-black.
(1)
a. True
b. False
1.11 Progesterone causes:
(1)
a. Rapid desquamation of the upper layer of epithelium
b. Deposition of glycogen within the vaginal epithelium
c. Deposition of glycogen within the vaginal and gastric epithelium
1.12 Mucus of vaginal discharge is produced by:
(1)
a. Glands in the uterus
b. Glands of the cervix
c. Glands of the uterus and cervix
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1.13 Only aircons and not extraction fans are sufficient for the cytology preparation (1)
room.
a. False
b. True
1.14 Process all cytology specimens in a laminar flow cabinet
(1)
a. False
b. True
1.15 Not every specimen received in the Cytology Laboratory is considered highly
infectious
(1)
a. False
b. True
QUESTION 2
[20]
2.1 Briefly describe the following:
2.1.1 Nucleocytoplasmic ratio
(1)
2.1.2. Chromatin pattern
(2)
2.1.3. Pyknotic
(1)
2.1.4 Vesicular
(1)
2.1.5 Pleomorphism
(1)
2.1.6 Anisonucleosis
(1)
2.1.7. Navicular cells
(1)
2.1.8 Cytolysis
(2)
2.2 Name the epithelial tissue which lines each of the following:
2.2.1 Stomach
(1)
2.2.2 Nasopharynx
(1)
2.2.3. Mouth
(1)
2.2.4 Heart
(1)
2.2.5 Urinary system
(1)
2.2.6 Fallopian ducts
(1)
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2.3 Which Sex hormone plays an important role in the maturation of stratified squamous
epithelium of the female genital tract to:
2.3.1 Intermediate layer
(1)
2.3.2 Superficial layer
(1)
2.4 Indicate the Maturation Index pattern% for the following:
2.4.1 Child
(1)
2.4.2 Pregnancy
(1)
SECTION B (MARKS 25)
QUESTION 3
[25]
3.1 What are the main aspects of safety at Cytology Specimen reception
(5)
3.2
Propose the characteristics of a suitable/good fixative?
(10)
3.3
Write notes on Cytoplasmic stain of Papanicolaou Staining Technique.
(10)
SECTION C (MARKS 15)
QUESTION 4
[15]
4.1 Write short notes on the Bench Centrifuge used in the preparation of cytology
samples.
(10)
4.2 Outline the principle of Cytology Fixation.
(5)
SECTION D (MARKS 25)
QUESTION 5
[25]
5.1
What low-risk Human Papilloma Virus (HPV) types are associated with pre-
cancerous lesions of the cervix
(5)
5.2
Describe cytological findings for Human Papilloma Virus infection of the cervix. (10)
5.3
Describe diagnostic criteria of Non - Keratinizing Squamous Cell Carcinoma. (10)
End of examination